Low Copper intake can increase the risk of high serum cholesterol, coronary heart disease, irregular heartbeat, decreased pigmentation of skin vitiligo, premature graying hair, hernias, aneurysm, varicose veins, dermatitis, fatigue, anemia, anorexia, thyroid problems, allergies, poor healing, lowered immunity, arthritis and fragile bones, neutropenia, and mood & nervous disorders. Although higher copper levels support angiogenesis with most tumors, colon cancer often develops in the presence of insufficient cellular copper, calcium, and potassium levels. Menkes syndrome is a fatal disease usually affecting infants, and caused by faulty copper absorption... Full Text

Manganese may help with some symptoms of Parkinson's disease such as muscle rigidity and twitching...
Research shows that phytosterols such as beta-sitosterol may help normalize the function of natural killer cells and T-helper lymphocytes...
Iron deficiency may be suspect with some forms of ADHD. 84% of children with ADHD were found to have abnormally low levels of ferritin...
A high intake of B Vitamins can trigger heart palpitations, HBP, major complications in patients with congestive heart disease...